BDBM50188724 3-methyl-8-methoxy-5H-indeno[1,2-c]pyridazin-5-one::CHEMBL210626

SMILES: COc1ccc2C(=O)c3cc(C)nnc3-c2c1

InChI Key: InChIKey=XSAAXKYPHJXQGS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50188724   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50188724 (3-methyl-8-methoxy-5H-indeno[1,2-c]pyridazin-5-one...) Show SMILES COc1ccc2C(=O)c3cc(C)nnc3-c2c1 Show InChI InChI=1S/C13H10N2O2/c1-7-5-11-12(15-14-7)10-6-8(17-2)3-4-9(10)13(11)16/h3-6H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Facultés Universitaires N.D de la Paix Curated by ChEMBL					Assay Description Inhibition of MAO-B in rat brain mitochondria				J Med Chem 49: 3743-7 (2006) Article DOI: 10.1021/jm051091j BindingDB Entry DOI: 10.7270/Q2SF2VSN
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50188724 (3-methyl-8-methoxy-5H-indeno[1,2-c]pyridazin-5-one...) Show SMILES COc1ccc2C(=O)c3cc(C)nnc3-c2c1 Show InChI InChI=1S/C13H10N2O2/c1-7-5-11-12(15-14-7)10-6-8(17-2)3-4-9(10)13(11)16/h3-6H,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Facultés Universitaires N.D de la Paix Curated by ChEMBL					Assay Description Inhibition of MAO-A in rat brain mitochondria				J Med Chem 49: 3743-7 (2006) Article DOI: 10.1021/jm051091j BindingDB Entry DOI: 10.7270/Q2SF2VSN
					More data for this Ligand-Target Pair