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BDBM50188801 CHEMBL213620::ammonium N-{4-[2-(2-{[(tert-butoxy)carbonyl]amino}ethyl)-3-ethoxy-2-(methoxycarbonyl)-3-oxopropyl]phenyl}sulfamate

SMILES: CCOC(=O)C(CCNC(=O)OC(C)(C)C)(Cc1ccc(NS([O-])(=O)=O)cc1)C(=O)OC

InChI Key: InChIKey=NMLHTJNZGQJTJI-UHFFFAOYSA-M

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188801   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Receptor-type tyrosine-protein phosphatase beta (PTPβ)


(Homo sapiens (Human))
BDBM50188801
PNG
(CHEMBL213620 | ammonium N-{4-[2-(2-{[(tert-butoxy)...)
Show SMILES CCOC(=O)C(CCNC(=O)OC(C)(C)C)(Cc1ccc(NS([O-])(=O)=O)cc1)C(=O)OC
Show InChI InChI=1S/C20H30N2O9S/c1-6-30-17(24)20(16(23)29-5,11-12-21-18(25)31-19(2,3)4)13-14-7-9-15(10-8-14)22-32(26,27)28/h7-10,22H,6,11-13H2,1-5H3,(H,21,25)(H,26,27,28)/p-1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 90n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of HPTPbeta


Bioorg Med Chem Lett 16: 4252-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.05.074
BindingDB Entry DOI: 10.7270/Q2D50MK4
More data for this
Ligand-Target Pair