BDBM50188802 CHEMBL210180::ammonium N-[4-(2-{[(tert-butoxy)carbonyl]amino}-3-ethoxy-2-(methoxycarbonyl)-3-oxopropyl)phenyl]sulfamate
SMILES: CCOC(=O)C(Cc1ccc(NS([O-])(=O)=O)cc1)(NC(=O)OC(C)(C)C)C(=O)OC
InChI Key: InChIKey=UCDDEGDLIGIQQG-UHFFFAOYSA-M
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Receptor-type tyrosine-protein phosphatase beta (PTPβ) (Homo sapiens (Human)) | BDBM50188802![]() (CHEMBL210180 | ammonium N-[4-(2-{[(tert-butoxy)car...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of HPTPbeta | Bioorg Med Chem Lett 16: 4252-6 (2006) Article DOI: 10.1016/j.bmcl.2006.05.074 BindingDB Entry DOI: 10.7270/Q2D50MK4 | |||||||||||
More data for this Ligand-Target Pair |