BDBM50188985 5-chloro-2-(3-chlorophenyl)-3-(phenethylamino)indolizine-1-carbonitrile::CHEMBL384861

SMILES: Clc1cccc(c1)-c1c(C#N)c2cccc(Cl)n2c1NCCc1ccccc1

InChI Key: InChIKey=XXBWZBYLHOTYSY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188985   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropilin-1 (Homo sapiens (Human))	BDBM50188985 (5-chloro-2-(3-chlorophenyl)-3-(phenethylamino)indo...) Show SMILES Clc1cccc(c1)-c1c(C#N)c2cccc(Cl)n2c1NCCc1ccccc1 Show InChI InChI=1S/C23H17Cl2N3/c24-18-9-4-8-17(14-18)22-19(15-26)20-10-5-11-21(25)28(20)23(22)27-13-12-16-6-2-1-3-7-16/h1-11,14,27H,12-13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pierre Fabre Urologie Curated by ChEMBL					Assay Description Inhibition of VEGF165-NRP1 interaction by ELISA				Bioorg Med Chem Lett 16: 3998-4001 (2006) Article DOI: 10.1016/j.bmcl.2006.05.014 BindingDB Entry DOI: 10.7270/Q20Z72WD
					More data for this Ligand-Target Pair