BDBM50189855 2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]-6-(piperidin-1-yl)imidazo[1,2-b]pyridazine::CHEMBL207543

SMILES: Clc1ccc(cc1Cl)N1CCN(Cc2cn3nc(ccc3n2)N2CCCCC2)CC1

InChI Key: InChIKey=ACHQQXOLWIKHRK-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50189855   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50189855 (2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]-6-(...) Show SMILES Clc1ccc(cc1Cl)N1CCN(Cc2cn3nc(ccc3n2)N2CCCCC2)CC1 Show InChI InChI=1S/C22H26Cl2N6/c23-19-5-4-18(14-20(19)24)28-12-10-27(11-13-28)15-17-16-30-21(25-17)6-7-22(26-30)29-8-2-1-3-9-29/h4-7,14,16H,1-3,8-13,15H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Chimie Th�rapeutique Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membrane				J Med Chem 49: 3938-47 (2006) Article DOI: 10.1021/jm060166w BindingDB Entry DOI: 10.7270/Q20G3KZ5
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50189855 (2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]-6-(...) Show SMILES Clc1ccc(cc1Cl)N1CCN(Cc2cn3nc(ccc3n2)N2CCCCC2)CC1 Show InChI InChI=1S/C22H26Cl2N6/c23-19-5-4-18(14-20(19)24)28-12-10-27(11-13-28)15-17-16-30-21(25-17)6-7-22(26-30)29-8-2-1-3-9-29/h4-7,14,16H,1-3,8-13,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	710	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Chimie Th�rapeutique Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine receptor D2(short) in CHO cell membrane				J Med Chem 49: 3938-47 (2006) Article DOI: 10.1021/jm060166w BindingDB Entry DOI: 10.7270/Q20G3KZ5
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50189855 (2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]-6-(...) Show SMILES Clc1ccc(cc1Cl)N1CCN(Cc2cn3nc(ccc3n2)N2CCCCC2)CC1 Show InChI InChI=1S/C22H26Cl2N6/c23-19-5-4-18(14-20(19)24)28-12-10-27(11-13-28)15-17-16-30-21(25-17)6-7-22(26-30)29-8-2-1-3-9-29/h4-7,14,16H,1-3,8-13,15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	850	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Chimie Th�rapeutique Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine receptor D3 in CHO cell membrane				J Med Chem 49: 3938-47 (2006) Article DOI: 10.1021/jm060166w BindingDB Entry DOI: 10.7270/Q20G3KZ5
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50189855 (2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]-6-(...) Show SMILES Clc1ccc(cc1Cl)N1CCN(Cc2cn3nc(ccc3n2)N2CCCCC2)CC1 Show InChI InChI=1S/C22H26Cl2N6/c23-19-5-4-18(14-20(19)24)28-12-10-27(11-13-28)15-17-16-30-21(25-17)6-7-22(26-30)29-8-2-1-3-9-29/h4-7,14,16H,1-3,8-13,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Chimie Th�rapeutique Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine receptor D2(long) in CHO cell membrane				J Med Chem 49: 3938-47 (2006) Article DOI: 10.1021/jm060166w BindingDB Entry DOI: 10.7270/Q20G3KZ5
					More data for this Ligand-Target Pair
Dopamine D1 receptor (Sus scrofa)	BDBM50189855 (2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]-6-(...) Show SMILES Clc1ccc(cc1Cl)N1CCN(Cc2cn3nc(ccc3n2)N2CCCCC2)CC1 Show InChI InChI=1S/C22H26Cl2N6/c23-19-5-4-18(14-20(19)24)28-12-10-27(11-13-28)15-17-16-30-21(25-17)6-7-22(26-30)29-8-2-1-3-9-29/h4-7,14,16H,1-3,8-13,15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Chimie Th�rapeutique Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23990 from dopamine receptor D1 in porcine striatal membrane				J Med Chem 49: 3938-47 (2006) Article DOI: 10.1021/jm060166w BindingDB Entry DOI: 10.7270/Q20G3KZ5
					More data for this Ligand-Target Pair