BDBM50189896 CHEMBL3827624
SMILES: [Br-].CN(C)C(=O)Oc1c(C)[n+](C)cc2COC(OCc12)C(C)(C)C
InChI Key: InChIKey=MQBKTBSRSRNTJO-UHFFFAOYSA-M
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Cholinesterases (Homo sapiens (Human)) | BDBM50189896 (CHEMBL3827624) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human plasma BChE assessed as butyrylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2... | Bioorg Med Chem Lett 26: 4092-4 (2016) BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50189896 (CHEMBL3827624) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kazan (Volga region) Federal University Curated by ChEMBL | Assay Description Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by... | Bioorg Med Chem Lett 26: 4092-4 (2016) BindingDB Entry DOI: 10.7270/Q2BR8V31 | |||||||||||
More data for this Ligand-Target Pair |