BDBM50190177 CHEMBL3828609

SMILES: Cc1nc2ccccc2n1CC(=O)NNC(=O)Cc1ccccc1

InChI Key: InChIKey=PQEIJBAFFMEGPU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50190177   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50190177 (CHEMBL3828609) Show SMILES Cc1nc2ccccc2n1CC(=O)NNC(=O)Cc1ccccc1 Show InChI InChI=1S/C18H18N4O2/c1-13-19-15-9-5-6-10-16(15)22(13)12-18(24)21-20-17(23)11-14-7-3-2-4-8-14/h2-10H,11-12H2,1H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University) Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His-tagged GSK-3beta expressed in Escherichia coli using glycogen synthase-2 as substrate and ATP measured...				Bioorg Med Chem Lett 26: 4020-4 (2016) BindingDB Entry DOI: 10.7270/Q2639RP0
					More data for this Ligand-Target Pair