BDBM50190496 6-chloro-3-(1-phenylcyclopropyl)amino-4H-thieno[3,2-e]-1,2,4-thiadiazine1,1-dioxide::CHEMBL379292

SMILES: Clc1cc2N=C(NC3(CC3)c3ccccc3)NS(=O)(=O)c2s1

InChI Key: InChIKey=NSHQOOIHPDLZQY-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50190496   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 1 (Homo sapiens (Human))	BDBM50190496 (6-chloro-3-(1-phenylcyclopropyl)amino-4H-thieno[3,...) Show SMILES Clc1cc2N=C(NC3(CC3)c3ccccc3)NS(=O)(=O)c2s1 |t:4| Show InChI InChI=1S/C14H12ClN3O2S2/c15-11-8-10-12(21-11)22(19,20)18-13(16-10)17-14(6-7-14)9-4-2-1-3-5-9/h1-5,8H,6-7H2,(H2,16,17,18)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	810	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Repolarization of HEK293 cells expressing Kir6.2/SUR1 KATP channels				J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN
					More data for this Ligand-Target Pair