BDBM50191571 CHEMBL212766::N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)acetamide

SMILES: [#6]-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6@@H](-[#6]-[#6@@H]-1-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#8]-[#6]-c1ccc2ccccc2c1

InChI Key: InChIKey=WIUGVXOSBXINHH-UPRLRBBYSA-N

Data: 3 KI  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50191571   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50191571 (CHEMBL212766 | N-((R)-1-((2S,4R)-2-(3-guanidinopro...) Show SMILES [#6]-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6@@H](-[#6]-[#6@@H]-1-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#8]-[#6]-c1ccc2ccccc2c1 Show InChI InChI=1S/C30H37N5O3/c1-21(36)34-28(17-22-8-3-2-4-9-22)29(37)35-19-27(18-26(35)12-7-15-33-30(31)32)38-20-23-13-14-24-10-5-6-11-25(24)16-23/h2-6,8-11,13-14,16,26-28H,7,12,15,17-20H2,1H3,(H,34,36)(H4,31,32,33)/t26-,27+,28+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of europium labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells				J Med Chem 49: 4745-61 (2006) Article DOI: 10.1021/jm060384p BindingDB Entry DOI: 10.7270/Q29W0F4J
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50191571 (CHEMBL212766 | N-((R)-1-((2S,4R)-2-(3-guanidinopro...) Show SMILES [#6]-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6@@H](-[#6]-[#6@@H]-1-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#8]-[#6]-c1ccc2ccccc2c1 Show InChI InChI=1S/C30H37N5O3/c1-21(36)34-28(17-22-8-3-2-4-9-22)29(37)35-19-27(18-26(35)12-7-15-33-30(31)32)38-20-23-13-14-24-10-5-6-11-25(24)16-23/h2-6,8-11,13-14,16,26-28H,7,12,15,17-20H2,1H3,(H,34,36)(H4,31,32,33)/t26-,27+,28+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	289	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of europium labeled NDP-alpha-MSH from human MC3R expressed in HEK293 cells				J Med Chem 49: 4745-61 (2006) Article DOI: 10.1021/jm060384p BindingDB Entry DOI: 10.7270/Q29W0F4J
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50191571 (CHEMBL212766 | N-((R)-1-((2S,4R)-2-(3-guanidinopro...) Show SMILES [#6]-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6@@H](-[#6]-[#6@@H]-1-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#8]-[#6]-c1ccc2ccccc2c1 Show InChI InChI=1S/C30H37N5O3/c1-21(36)34-28(17-22-8-3-2-4-9-22)29(37)35-19-27(18-26(35)12-7-15-33-30(31)32)38-20-23-13-14-24-10-5-6-11-25(24)16-23/h2-6,8-11,13-14,16,26-28H,7,12,15,17-20H2,1H3,(H,34,36)(H4,31,32,33)/t26-,27+,28+/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	463	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of europium labeled NDP-alpha-MSH from human MC1R expressed in HEK293 cells				J Med Chem 49: 4745-61 (2006) Article DOI: 10.1021/jm060384p BindingDB Entry DOI: 10.7270/Q29W0F4J
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50191571 (CHEMBL212766 | N-((R)-1-((2S,4R)-2-(3-guanidinopro...) Show SMILES [#6]-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6@@H](-[#6]-[#6@@H]-1-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#8]-[#6]-c1ccc2ccccc2c1 Show InChI InChI=1S/C30H37N5O3/c1-21(36)34-28(17-22-8-3-2-4-9-22)29(37)35-19-27(18-26(35)12-7-15-33-30(31)32)38-20-23-13-14-24-10-5-6-11-25(24)16-23/h2-6,8-11,13-14,16,26-28H,7,12,15,17-20H2,1H3,(H,34,36)(H4,31,32,33)/t26-,27+,28+/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	232	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human MC1R transfected in HEK293 cells				J Med Chem 49: 4745-61 (2006) Article DOI: 10.1021/jm060384p BindingDB Entry DOI: 10.7270/Q29W0F4J
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50191571 (CHEMBL212766 | N-((R)-1-((2S,4R)-2-(3-guanidinopro...) Show SMILES [#6]-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6@@H](-[#6]-[#6@@H]-1-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#8]-[#6]-c1ccc2ccccc2c1 Show InChI InChI=1S/C30H37N5O3/c1-21(36)34-28(17-22-8-3-2-4-9-22)29(37)35-19-27(18-26(35)12-7-15-33-30(31)32)38-20-23-13-14-24-10-5-6-11-25(24)16-23/h2-6,8-11,13-14,16,26-28H,7,12,15,17-20H2,1H3,(H,34,36)(H4,31,32,33)/t26-,27+,28+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.38E+3	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human MC3R transfected in HEK293 cells				J Med Chem 49: 4745-61 (2006) Article DOI: 10.1021/jm060384p BindingDB Entry DOI: 10.7270/Q29W0F4J
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50191571 (CHEMBL212766 | N-((R)-1-((2S,4R)-2-(3-guanidinopro...) Show SMILES [#6]-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6@@H](-[#6]-[#6@@H]-1-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#8]-[#6]-c1ccc2ccccc2c1 Show InChI InChI=1S/C30H37N5O3/c1-21(36)34-28(17-22-8-3-2-4-9-22)29(37)35-19-27(18-26(35)12-7-15-33-30(31)32)38-20-23-13-14-24-10-5-6-11-25(24)16-23/h2-6,8-11,13-14,16,26-28H,7,12,15,17-20H2,1H3,(H,34,36)(H4,31,32,33)/t26-,27+,28+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	317	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human MC4R transfected in HEK293 cells				J Med Chem 49: 4745-61 (2006) Article DOI: 10.1021/jm060384p BindingDB Entry DOI: 10.7270/Q29W0F4J
					More data for this Ligand-Target Pair