BDBM50191761 4'-fluoro-biphenyl-4-carboxylic acid [3-(4-hydroxy-piperidin-1-ylmethyl)-quinolin-8-ylmethyl]-amide::CHEMBL214667
SMILES: OC1CCN(Cc2cnc3c(CNC(=O)c4ccc(cc4)-c4ccc(F)cc4)cccc3c2)CC1
InChI Key: InChIKey=OLFNWPFUFOIYFQ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Melanin-concentrating hormone receptor (Homo sapiens (Human)) | BDBM50191761![]() (4'-fluoro-biphenyl-4-carboxylic acid [3-(4-hydroxy...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 195 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Binding affinity to MCHR1 by radioligand binding assay | Bioorg Med Chem Lett 16: 5207-11 (2006) Article DOI: 10.1016/j.bmcl.2006.07.006 BindingDB Entry DOI: 10.7270/Q2SX6CV3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50191761![]() (4'-fluoro-biphenyl-4-carboxylic acid [3-(4-hydroxy...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine from 5HT2C receptor | Bioorg Med Chem Lett 16: 5207-11 (2006) Article DOI: 10.1016/j.bmcl.2006.07.006 BindingDB Entry DOI: 10.7270/Q2SX6CV3 | |||||||||||
More data for this Ligand-Target Pair |