BDBM50192180 3,5-dimethoxy-N-(2,2,6,6-tetramethyl-1-(naphthalen-2-ylmethyl)piperidin-4-yl)benzamide::CHEMBL385875
SMILES: COc1cc(OC)cc(c1)C(=O)NC1CC(C)(C)N(Cc2ccc3ccccc3c2)C(C)(C)C1
InChI Key: InChIKey=RAOXMFMKGZYCHJ-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50192180![]() (3,5-dimethoxy-N-(2,2,6,6-tetramethyl-1-(naphthalen...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding activity against human MCH-R1 | Bioorg Med Chem Lett 16: 5445-50 (2006) Article DOI: 10.1016/j.bmcl.2006.07.053 BindingDB Entry DOI: 10.7270/Q2CR5T0F | |||||||||||
More data for this Ligand-Target Pair |