BDBM50192225 3-(4-tert-butylphenyl)-4-cyano-5-(methylthio)furan-2-carboxylic acid::CHEMBL216478

SMILES: CSc1oc(C(O)=O)c(c1C#N)-c1ccc(cc1)C(C)(C)C

InChI Key: InChIKey=OPXKCSMQHPTQDF-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192225   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic AMPA (Homo sapiens (Human))	BDBM50192225 (3-(4-tert-butylphenyl)-4-cyano-5-(methylthio)furan...) Show SMILES CSc1oc(C(O)=O)c(c1C#N)-c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C17H17NO3S/c1-17(2,3)11-7-5-10(6-8-11)13-12(9-18)16(22-4)21-14(13)15(19)20/h5-8H,1-4H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	1.98E+3	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic AMPA (Homo sapiens (Human))	BDBM50192225 (3-(4-tert-butylphenyl)-4-cyano-5-(methylthio)furan...) Show SMILES CSc1oc(C(O)=O)c(c1C#N)-c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C17H17NO3S/c1-17(2,3)11-7-5-10(6-8-11)13-12(9-18)16(22-4)21-14(13)15(19)20/h5-8H,1-4H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair