BDBM50192534 1-(5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)-2-(p-tolyloxy)phenyl)-3-(3-fluorophenyl)urea::CHEMBL386117

SMILES: Cc1ccc(Oc2ccc(cc2NC(=O)Nc2cccc(F)c2)C(=O)NCCN2CCCC2)cc1

InChI Key: InChIKey=ZYJQVJKEBFTNEB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192534   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50192534 (1-(5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)-2-(p-to...) Show SMILES Cc1ccc(Oc2ccc(cc2NC(=O)Nc2cccc(F)c2)C(=O)NCCN2CCCC2)cc1 Show InChI InChI=1S/C27H29FN4O3/c1-19-7-10-23(11-8-19)35-25-12-9-20(26(33)29-13-16-32-14-2-3-15-32)17-24(25)31-27(34)30-22-6-4-5-21(28)18-22/h4-12,17-18H,2-3,13-16H2,1H3,(H,29,33)(H2,30,31,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of [125I]MCH binding to human MCHR1 expressed in HEK293 cells by HT-SPA				Bioorg Med Chem Lett 16: 5066-72 (2006) Article DOI: 10.1016/j.bmcl.2006.07.040 BindingDB Entry DOI: 10.7270/Q2FJ2GD3
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50192534 (1-(5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)-2-(p-to...) Show SMILES Cc1ccc(Oc2ccc(cc2NC(=O)Nc2cccc(F)c2)C(=O)NCCN2CCCC2)cc1 Show InChI InChI=1S/C27H29FN4O3/c1-19-7-10-23(11-8-19)35-25-12-9-20(26(33)29-13-16-32-14-2-3-15-32)17-24(25)31-27(34)30-22-6-4-5-21(28)18-22/h4-12,17-18H,2-3,13-16H2,1H3,(H,29,33)(H2,30,31,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of [125I]MCH binding to rat MCHR1 expressed in HEK293 cells by HT-SPA				Bioorg Med Chem Lett 16: 5066-72 (2006) Article DOI: 10.1016/j.bmcl.2006.07.040 BindingDB Entry DOI: 10.7270/Q2FJ2GD3
					More data for this Ligand-Target Pair