BDBM50192570 (R)-4-(2-oxo-1,2-dihydronaphtho[1,2-d]imidazol-3-yl)-N-(2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)piperidine-1-carboxamide::CHEMBL384539

SMILES: FC(F)(F)CN1c2ccccc2C(=N[C@@H](NC(=O)N2CCC(CC2)n2c3ccc4ccccc4c3[nH]c2=O)C1=O)c1ccccc1

InChI Key: InChIKey=LEWJHLVBGYAYCA-PMERELPUSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192570   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50192570 ((R)-4-(2-oxo-1,2-dihydronaphtho[1,2-d]imidazol-3-y...) Show SMILES FC(F)(F)CN1c2ccccc2C(=N[C@@H](NC(=O)N2CCC(CC2)n2c3ccc4ccccc4c3[nH]c2=O)C1=O)c1ccccc1 |c:13| Show InChI InChI=1S/C34H29F3N6O3/c35-34(36,37)20-42-26-13-7-6-12-25(26)28(22-9-2-1-3-10-22)38-30(31(42)44)40-32(45)41-18-16-23(17-19-41)43-27-15-14-21-8-4-5-11-24(21)29(27)39-33(43)46/h1-15,23,30H,16-20H2,(H,39,46)(H,40,45)/t30-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]CGRP from human recombinant CGRP receptor				Bioorg Med Chem Lett 16: 5052-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.044 BindingDB Entry DOI: 10.7270/Q29S1QNX
					More data for this Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50192570 ((R)-4-(2-oxo-1,2-dihydronaphtho[1,2-d]imidazol-3-y...) Show SMILES FC(F)(F)CN1c2ccccc2C(=N[C@@H](NC(=O)N2CCC(CC2)n2c3ccc4ccccc4c3[nH]c2=O)C1=O)c1ccccc1 |c:13| Show InChI InChI=1S/C34H29F3N6O3/c35-34(36,37)20-42-26-13-7-6-12-25(26)28(22-9-2-1-3-10-22)38-30(31(42)44)40-32(45)41-18-16-23(17-19-41)43-27-15-14-21-8-4-5-11-24(21)29(27)39-33(43)46/h1-15,23,30H,16-20H2,(H,39,46)(H,40,45)/t30-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	369	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production				Bioorg Med Chem Lett 16: 5052-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.044 BindingDB Entry DOI: 10.7270/Q29S1QNX
					More data for this Ligand-Target Pair