BDBM50192614 5,6-difluoro-N-(3-(4-methylpiperazin-1-yl)propyl)-N-((1R,3R,6R)-6-(3-(pyrrolidin-1-ylmethyl)phenyl)bicyclo[4.1.0]heptan-3-yl)-1H-benzo[d]imidazol-2-amine::CHEMBL386311

SMILES: CN1CCN(CCCN([C@@H]2CC[C@@]3(C[C@@H]3C2)c2cccc(CN3CCCC3)c2)c2nc3cc(F)c(F)cc3[nH]2)CC1

InChI Key: InChIKey=YBAMUENHBJVFDO-CLTMYIMISA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50192614   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50192614 (5,6-difluoro-N-(3-(4-methylpiperazin-1-yl)propyl)-...) Show SMILES CN1CCN(CCCN([C@@H]2CC[C@@]3(C[C@@H]3C2)c2cccc(CN3CCCC3)c2)c2nc3cc(F)c(F)cc3[nH]2)CC1 Show InChI InChI=1S/C33H44F2N6/c1-38-14-16-39(17-15-38)12-5-13-41(32-36-30-20-28(34)29(35)21-31(30)37-32)27-8-9-33(22-26(33)19-27)25-7-4-6-24(18-25)23-40-10-2-3-11-40/h4,6-7,18,20-21,26-27H,2-3,5,8-17,19,22-23H2,1H3,(H,36,37)/t26-,27+,33+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding activity against human MCH-R1				Bioorg Med Chem Lett 16: 5427-31 (2006) Article DOI: 10.1016/j.bmcl.2006.07.058 BindingDB Entry DOI: 10.7270/Q228076K
					More data for this Ligand-Target Pair