BDBM50193853 (R)-4-(5-chloro-1H-indole-2-sulfonyl)-1-[4-(N,N-dimethyl-carbamimidoyl)-benzyl]-6-oxo-piperazine-2-carboxylic acid::CHEMBL222013

SMILES: CN(C)C(=N)c1ccc(CN2[C@H](CN(CC2=O)S(=O)(=O)c2cc3cc(Cl)ccc3[nH]2)C(O)=O)cc1

InChI Key: InChIKey=PJBWISWKLGKRHX-LJQANCHMSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50193853   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50193853 ((R)-4-(5-chloro-1H-indole-2-sulfonyl)-1-[4-(N,N-di...) Show SMILES CN(C)C(=N)c1ccc(CN2[C@H](CN(CC2=O)S(=O)(=O)c2cc3cc(Cl)ccc3[nH]2)C(O)=O)cc1 Show InChI InChI=1S/C23H24ClN5O5S/c1-27(2)22(25)15-5-3-14(4-6-15)11-29-19(23(31)32)12-28(13-21(29)30)35(33,34)20-10-16-9-17(24)7-8-18(16)26-20/h3-10,19,25-26H,11-13H2,1-2H3,(H,31,32)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Portola Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from human ERG potassium channel expressed in HEK293 cells				Bioorg Med Chem Lett 16: 5507-12 (2006) Article DOI: 10.1016/j.bmcl.2006.08.039 BindingDB Entry DOI: 10.7270/Q2SF2X05
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