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SMILES: CN(CCCC(O)=O)C(=N)c1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1

InChI Key: InChIKey=OOSPJTCEPLZEPX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50193855   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))		BDBM50193855
PNG
(4-({4-[4-chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)...)
Show SMILES CN(CCCC(O)=O)C(=N)c1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1
Show InChI InChI=1S/C25H23Cl2N5O4/c1-32(12-2-3-22(33)34)23(28)15-4-6-16(7-5-15)24(35)30-20-10-8-17(26)13-19(20)25(36)31-21-11-9-18(27)14-29-21/h4-11,13-14,28H,2-3,12H2,1H3,(H,30,35)(H,33,34)(H,29,31,36)
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Article
PubMed
 1.40E+3n/an/an/an/an/an/an/an/a



Portola Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]dofetilide from human ERG potassium channel expressed in HEK293 cells

Bioorg Med Chem Lett 16: 5507-12 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.039
BindingDB Entry DOI: 10.7270/Q2SF2X05
More data for this
Ligand-Target Pair