BDBM50193858 CHEMBL218609::N-(4-chloro-2-(5-chloropyridin-2-ylcarbamoyl)phenyl)-4-(N,N-dimethylcarbamimidoyl)-2-(piperidin-1-yl)benzamide::N-{4-chloro-2-[(5-chloropyridin-2-yl)carbamoyl]phenyl}-4-(N,N-dimethylcarbamimidoyl)-2-(piperidin-1-yl)benzamide

SMILES: CN(C)C(=N)c1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)c(c1)N1CCCCC1

InChI Key: InChIKey=IOOYDBYUMRWAKN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50193858   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50193858 (CHEMBL218609 | N-(4-chloro-2-(5-chloropyridin-2-yl...) Show SMILES CN(C)C(=N)c1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)c(c1)N1CCCCC1 Show InChI InChI=1S/C27H28Cl2N6O2/c1-34(2)25(30)17-6-9-20(23(14-17)35-12-4-3-5-13-35)26(36)32-22-10-7-18(28)15-21(22)27(37)33-24-11-8-19(29)16-31-24/h6-11,14-16,30H,3-5,12-13H2,1-2H3,(H,32,36)(H,31,33,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Portola Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from human ERG potassium channel expressed in HEK293 cells				Bioorg Med Chem Lett 16: 5507-12 (2006) Article DOI: 10.1016/j.bmcl.2006.08.039 BindingDB Entry DOI: 10.7270/Q2SF2X05
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