BDBM50193865 2-(3-cyano-naphthalen-2-yl)-5-methyl-2H-pyrazole-3-carboxylic acid [4-(imino-pyrrolidin-1-yl-methyl)-phenyl]-amide::CHEMBL220704

SMILES: Cc1cc(C(=O)Nc2ccc(cc2)C(=N)N2CCCC2)n(n1)-c1cc2ccccc2cc1C#N

InChI Key: InChIKey=OMQZKXISGKXPTB-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50193865   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50193865 (2-(3-cyano-naphthalen-2-yl)-5-methyl-2H-pyrazole-3...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2)C(=N)N2CCCC2)n(n1)-c1cc2ccccc2cc1C#N Show InChI InChI=1S/C27H24N6O/c1-18-14-25(33(31-18)24-16-21-7-3-2-6-20(21)15-22(24)17-28)27(34)30-23-10-8-19(9-11-23)26(29)32-12-4-5-13-32/h2-3,6-11,14-16,29H,4-5,12-13H2,1H3,(H,30,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Portola Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from human ERG potassium channel expressed in HEK293 cells				Bioorg Med Chem Lett 16: 5507-12 (2006) Article DOI: 10.1016/j.bmcl.2006.08.039 BindingDB Entry DOI: 10.7270/Q2SF2X05
					More data for this Ligand-Target Pair