BDBM50194004 CHEMBL218746::N-((S)-1-(4-chlorophenyl)ethyl)-2-(3H-imidazo[4,5-c]pyridin-3-yl)pyrimidin-4-amine

SMILES: C[C@H](Nc1ccnc(n1)-n1cnc2ccncc12)c1ccc(Cl)cc1

InChI Key: InChIKey=YHZMGOWCNDVVNF-LBPRGKRZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50194004   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50194004 (CHEMBL218746 | N-((S)-1-(4-chlorophenyl)ethyl)-2-(...) Show SMILES C[C@H](Nc1ccnc(n1)-n1cnc2ccncc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H15ClN6/c1-12(13-2-4-14(19)5-3-13)23-17-7-9-21-18(24-17)25-11-22-15-6-8-20-10-16(15)25/h2-12H,1H3,(H,21,23,24)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of JAK2				Bioorg Med Chem Lett 16: 5633-8 (2006) Article DOI: 10.1016/j.bmcl.2006.08.022 BindingDB Entry DOI: 10.7270/Q2J1040K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50194004 (CHEMBL218746 | N-((S)-1-(4-chlorophenyl)ethyl)-2-(...) Show SMILES C[C@H](Nc1ccnc(n1)-n1cnc2ccncc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H15ClN6/c1-12(13-2-4-14(19)5-3-13)23-17-7-9-21-18(24-17)25-11-22-15-6-8-20-10-16(15)25/h2-12H,1H3,(H,21,23,24)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of JAK3				Bioorg Med Chem Lett 16: 5633-8 (2006) Article DOI: 10.1016/j.bmcl.2006.08.022 BindingDB Entry DOI: 10.7270/Q2J1040K
					More data for this Ligand-Target Pair