BDBM50194010 6-(4-(dimethylamino)phenyl)-2-(3H-imidazo[4,5-c]pyridin-3-yl)-N-((S)-1-phenylethyl)pyrimidin-4-amine::CHEMBL384820

SMILES: C[C@H](Nc1cc(nc(n1)-n1cnc2ccncc12)-c1ccc(cc1)N(C)C)c1ccccc1

InChI Key: InChIKey=CMXVRFDAZVLFOZ-SFHVURJKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50194010   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50194010 (6-(4-(dimethylamino)phenyl)-2-(3H-imidazo[4,5-c]py...) Show SMILES C[C@H](Nc1cc(nc(n1)-n1cnc2ccncc12)-c1ccc(cc1)N(C)C)c1ccccc1 Show InChI InChI=1S/C26H25N7/c1-18(19-7-5-4-6-8-19)29-25-15-23(20-9-11-21(12-10-20)32(2)3)30-26(31-25)33-17-28-22-13-14-27-16-24(22)33/h4-18H,1-3H3,(H,29,30,31)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of JAK3				Bioorg Med Chem Lett 16: 5633-8 (2006) Article DOI: 10.1016/j.bmcl.2006.08.022 BindingDB Entry DOI: 10.7270/Q2J1040K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50194010 (6-(4-(dimethylamino)phenyl)-2-(3H-imidazo[4,5-c]py...) Show SMILES C[C@H](Nc1cc(nc(n1)-n1cnc2ccncc12)-c1ccc(cc1)N(C)C)c1ccccc1 Show InChI InChI=1S/C26H25N7/c1-18(19-7-5-4-6-8-19)29-25-15-23(20-9-11-21(12-10-20)32(2)3)30-26(31-25)33-17-28-22-13-14-27-16-24(22)33/h4-18H,1-3H3,(H,29,30,31)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of JAK2				Bioorg Med Chem Lett 16: 5633-8 (2006) Article DOI: 10.1016/j.bmcl.2006.08.022 BindingDB Entry DOI: 10.7270/Q2J1040K
					More data for this Ligand-Target Pair