BDBM50194086 6-methyl-9a-(2-naphthylmethyl)-8,9,9a,10-tetrahydroindeno[2,1-e]indazol-7(3H)-one::CHEMBL438256

SMILES: CC1=C2c3ccc4[nH]ncc4c3CC2(Cc2ccc3ccccc3c2)CCC1=O

InChI Key: InChIKey=MNNXZGKKWOQTBW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50194086   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM50194086 (6-methyl-9a-(2-naphthylmethyl)-8,9,9a,10-tetrahydr...) Show SMILES CC1=C2c3ccc4[nH]ncc4c3CC2(Cc2ccc3ccccc3c2)CCC1=O |c:1| Show InChI InChI=1S/C26H22N2O/c1-16-24(29)10-11-26(13-17-6-7-18-4-2-3-5-19(18)12-17)14-21-20(25(16)26)8-9-23-22(21)15-27-28-23/h2-9,12,15H,10-11,13-14H2,1H3,(H,27,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
IRBM (Merck Research Laboratories Rome) Curated by ChEMBL					Assay Description Binding affinity to ERalpha L384M/M421G mutant				J Med Chem 49: 5404-7 (2006) Article DOI: 10.1021/jm060516e BindingDB Entry DOI: 10.7270/Q2DB81GH
					More data for this Ligand-Target Pair