BDBM50195047 CHEMBL376031::N-(4-(2-(3-(trifluoromethoxy)phenoxy)thiazol-5-yl)but-3-yn-2-yl)acetamide

SMILES: CC(NC(C)=O)C#Cc1cnc(Oc2cccc(OC(F)(F)F)c2)s1

InChI Key: InChIKey=WGRJFUSSLAVXMH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50195047   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 1 (ACC1) (Homo sapiens (Human))	BDBM50195047 (CHEMBL376031 | N-(4-(2-(3-(trifluoromethoxy)phenox...) Show SMILES CC(NC(C)=O)C#Cc1cnc(Oc2cccc(OC(F)(F)F)c2)s1 Show InChI InChI=1S/C16H13F3N2O3S/c1-10(21-11(2)22)6-7-14-9-20-15(25-14)23-12-4-3-5-13(8-12)24-16(17,18)19/h3-5,8-10H,1-2H3,(H,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant ACC1				Bioorg Med Chem Lett 16: 6078-81 (2006) Article DOI: 10.1016/j.bmcl.2006.08.100 BindingDB Entry DOI: 10.7270/Q2RJ4J4W
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM50195047 (CHEMBL376031 | N-(4-(2-(3-(trifluoromethoxy)phenox...) Show SMILES CC(NC(C)=O)C#Cc1cnc(Oc2cccc(OC(F)(F)F)c2)s1 Show InChI InChI=1S/C16H13F3N2O3S/c1-10(21-11(2)22)6-7-14-9-20-15(25-14)23-12-4-3-5-13(8-12)24-16(17,18)19/h3-5,8-10H,1-2H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant ACC2				Bioorg Med Chem Lett 16: 6078-81 (2006) Article DOI: 10.1016/j.bmcl.2006.08.100 BindingDB Entry DOI: 10.7270/Q2RJ4J4W
					More data for this Ligand-Target Pair