Found 3 hits for monomerid = 50195175 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Glycine transporter 2
(Homo sapiens (Human)) | BDBM50195175
(CHEMBL223491 | N-((4-(3-aminoazetidine-1-carbonyl)...)Show SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2ccc(Cl)cc2Cl)(CC1)C(=O)N1CC(N)C1 Show InChI InChI=1S/C20H28Cl2N4O4S/c1-2-9-31(29,30)26-7-5-20(6-8-26,19(28)25-11-15(23)12-25)13-24-18(27)16-4-3-14(21)10-17(16)22/h3-4,10,15H,2,5-9,11-13,23H2,1H3,(H,24,27) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck and Co.
Curated by ChEMBL
| Assay Description Inhibition of human GlyT2 |
Bioorg Med Chem Lett 16: 5968-72 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.131 BindingDB Entry DOI: 10.7270/Q2C82B31 |
More data for this Ligand-Target Pair | |
Glycine transporter 1
(Homo sapiens (Human)) | BDBM50195175
(CHEMBL223491 | N-((4-(3-aminoazetidine-1-carbonyl)...)Show SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2ccc(Cl)cc2Cl)(CC1)C(=O)N1CC(N)C1 Show InChI InChI=1S/C20H28Cl2N4O4S/c1-2-9-31(29,30)26-7-5-20(6-8-26,19(28)25-11-15(23)12-25)13-24-18(27)16-4-3-14(21)10-17(16)22/h3-4,10,15H,2,5-9,11-13,23H2,1H3,(H,24,27) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 109 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck and Co.
Curated by ChEMBL
| Assay Description Inhibition of human GlyT1 |
Bioorg Med Chem Lett 16: 5968-72 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.131 BindingDB Entry DOI: 10.7270/Q2C82B31 |
More data for this Ligand-Target Pair | |
Sodium- and chloride-dependent taurine transporter
(Homo sapiens (Human)) | BDBM50195175
(CHEMBL223491 | N-((4-(3-aminoazetidine-1-carbonyl)...)Show SMILES CCCS(=O)(=O)N1CCC(CNC(=O)c2ccc(Cl)cc2Cl)(CC1)C(=O)N1CC(N)C1 Show InChI InChI=1S/C20H28Cl2N4O4S/c1-2-9-31(29,30)26-7-5-20(6-8-26,19(28)25-11-15(23)12-25)13-24-18(27)16-4-3-14(21)10-17(16)22/h3-4,10,15H,2,5-9,11-13,23H2,1H3,(H,24,27) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck and Co.
Curated by ChEMBL
| Assay Description Inhibition of human TauT |
Bioorg Med Chem Lett 16: 5968-72 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.131 BindingDB Entry DOI: 10.7270/Q2C82B31 |
More data for this Ligand-Target Pair | |