BDBM50196400 CHEMBL3979588

SMILES: Fc1cc(Oc2ccc(cc2)C#N)cc(c1)N1Cc2ccccc2S1(=O)=O

InChI Key: InChIKey=AEESKWDRFZVEKJ-UHFFFAOYSA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50196400   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 4 (Homo sapiens (Human))	BDBM50196400 (CHEMBL3979588) Show SMILES Fc1cc(Oc2ccc(cc2)C#N)cc(c1)N1Cc2ccccc2S1(=O)=O Show InChI InChI=1S/C20H13FN2O3S/c21-16-9-17(23-13-15-3-1-2-4-20(15)27(23,24)25)11-19(10-16)26-18-7-5-14(12-22)6-8-18/h1-11H,13H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at C-terminal YFP-tagged human FFA4 expressed in HEK293 cells in presence of coelentrazine h by BRET based beta-arrestin-2 interacti...				J Med Chem 59: 8868-8878 (2016) Article DOI: 10.1021/acs.jmedchem.6b00685 BindingDB Entry DOI: 10.7270/Q2C53NS2
					More data for this Ligand-Target Pair
Free fatty acid receptor 4 (Homo sapiens (Human))	BDBM50196400 (CHEMBL3979588) Show SMILES Fc1cc(Oc2ccc(cc2)C#N)cc(c1)N1Cc2ccccc2S1(=O)=O Show InChI InChI=1S/C20H13FN2O3S/c21-16-9-17(23-13-15-3-1-2-4-20(15)27(23,24)25)11-19(10-16)26-18-7-5-14(12-22)6-8-18/h1-11H,13H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.34E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA4 expressed in human Flp-In T-REx293 cells by Fura2-AM dye based calcium mobilization assay				J Med Chem 59: 8868-8878 (2016) Article DOI: 10.1021/acs.jmedchem.6b00685 BindingDB Entry DOI: 10.7270/Q2C53NS2
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50196400 (CHEMBL3979588) Show SMILES Fc1cc(Oc2ccc(cc2)C#N)cc(c1)N1Cc2ccccc2S1(=O)=O Show InChI InChI=1S/C20H13FN2O3S/c21-16-9-17(23-13-15-3-1-2-4-20(15)27(23,24)25)11-19(10-16)26-18-7-5-14(12-22)6-8-18/h1-11H,13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	617	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Antagonist activity against human FFA1 expressed in human Flp-In T-REx293 cells assessed as as reduction in TUG424-induced response by Fura2-AM dye b...				J Med Chem 59: 8868-8878 (2016) Article DOI: 10.1021/acs.jmedchem.6b00685 BindingDB Entry DOI: 10.7270/Q2C53NS2
					More data for this Ligand-Target Pair