BDBM50196657 12-(3-adamantan-1-yl-ureido)-dodecanoic acid 2-chloro-benzyl ester::CHEMBL225271

SMILES: Clc1ccccc1COC(=O)CCCCCCCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2

InChI Key: InChIKey=YIHHIHHLBKORMX-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50196657   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Soluble epoxide hydrolase (sEH) (Mus musculus (Mouse))	BDBM50196657 (12-(3-adamantan-1-yl-ureido)-dodecanoic acid 2-chl...) Show SMILES Clc1ccccc1COC(=O)CCCCCCCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:25:26:29:33.32.31,THB:27:28:31:35.26.34,27:26:29.28.33:31,34:26:29:33.32.31,34:32:29:35.27.26| Show InChI InChI=1S/C30H45ClN2O3/c31-27-13-10-9-12-26(27)22-36-28(34)14-8-6-4-2-1-3-5-7-11-15-32-29(35)33-30-19-23-16-24(20-30)18-25(17-23)21-30/h9-10,12-13,23-25H,1-8,11,14-22H2,(H2,32,33,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Department of Entomology and University of California Davis Cancer Center Curated by ChEMBL					Assay Description Inhibition of mouse soluble epoxide hydrolase by spectrometric based assay				Bioorg Med Chem 15: 312-23 (2006) Article DOI: 10.1016/j.bmc.2006.09.057 BindingDB Entry DOI: 10.7270/Q26D5SNJ
					More data for this Ligand-Target Pair
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50196657 (12-(3-adamantan-1-yl-ureido)-dodecanoic acid 2-chl...) Show SMILES Clc1ccccc1COC(=O)CCCCCCCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:25:26:29:33.32.31,THB:27:28:31:35.26.34,27:26:29.28.33:31,34:26:29:33.32.31,34:32:29:35.27.26| Show InChI InChI=1S/C30H45ClN2O3/c31-27-13-10-9-12-26(27)22-36-28(34)14-8-6-4-2-1-3-5-7-11-15-32-29(35)33-30-19-23-16-24(20-30)18-25(17-23)21-30/h9-10,12-13,23-25H,1-8,11,14-22H2,(H2,32,33,35)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Department of Entomology and University of California Davis Cancer Center Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase by spectrometric based assay				Bioorg Med Chem 15: 312-23 (2006) Article DOI: 10.1016/j.bmc.2006.09.057 BindingDB Entry DOI: 10.7270/Q26D5SNJ
					More data for this Ligand-Target Pair
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50196657 (12-(3-adamantan-1-yl-ureido)-dodecanoic acid 2-chl...) Show SMILES Clc1ccccc1COC(=O)CCCCCCCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:25:26:29:33.32.31,THB:27:28:31:35.26.34,27:26:29.28.33:31,34:26:29:33.32.31,34:32:29:35.27.26| Show InChI InChI=1S/C30H45ClN2O3/c31-27-13-10-9-12-26(27)22-36-28(34)14-8-6-4-2-1-3-5-7-11-15-32-29(35)33-30-19-23-16-24(20-30)18-25(17-23)21-30/h9-10,12-13,23-25H,1-8,11,14-22H2,(H2,32,33,35)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Department of Entomology and University of California Davis Cancer Center Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase by fluorescent based assay				Bioorg Med Chem 15: 312-23 (2006) Article DOI: 10.1016/j.bmc.2006.09.057 BindingDB Entry DOI: 10.7270/Q26D5SNJ
					More data for this Ligand-Target Pair