BDBM50196659 12-(3-adamantan-1-yl-ureido)-dodecanoic acid methyl ester::CHEMBL224357

SMILES: COC(=O)CCCCCCCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2

InChI Key: InChIKey=LPMYMQCMDMYOIV-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50196659   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50196659 (12-(3-adamantan-1-yl-ureido)-dodecanoic acid methy...) Show SMILES COC(=O)CCCCCCCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:18:19:22:26.25.24,THB:20:21:24:28.19.27,20:19:22.21.26:24,27:19:22:26.25.24,27:25:22:28.20.19| Show InChI InChI=1S/C24H42N2O3/c1-29-22(27)11-9-7-5-3-2-4-6-8-10-12-25-23(28)26-24-16-19-13-20(17-24)15-21(14-19)18-24/h19-21H,2-18H2,1H3,(H2,25,26,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Department of Entomology and University of California Davis Cancer Center Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase by fluorescent based assay				Bioorg Med Chem 15: 312-23 (2006) Article DOI: 10.1016/j.bmc.2006.09.057 BindingDB Entry DOI: 10.7270/Q26D5SNJ
					More data for this Ligand-Target Pair
Soluble epoxide hydrolase (sEH) (Mus musculus (Mouse))	BDBM50196659 (12-(3-adamantan-1-yl-ureido)-dodecanoic acid methy...) Show SMILES COC(=O)CCCCCCCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:18:19:22:26.25.24,THB:20:21:24:28.19.27,20:19:22.21.26:24,27:19:22:26.25.24,27:25:22:28.20.19| Show InChI InChI=1S/C24H42N2O3/c1-29-22(27)11-9-7-5-3-2-4-6-8-10-12-25-23(28)26-24-16-19-13-20(17-24)15-21(14-19)18-24/h19-21H,2-18H2,1H3,(H2,25,26,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Department of Entomology and University of California Davis Cancer Center Curated by ChEMBL					Assay Description Inhibition of mouse soluble epoxide hydrolase by spectrometric based assay				Bioorg Med Chem 15: 312-23 (2006) Article DOI: 10.1016/j.bmc.2006.09.057 BindingDB Entry DOI: 10.7270/Q26D5SNJ
					More data for this Ligand-Target Pair
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50196659 (12-(3-adamantan-1-yl-ureido)-dodecanoic acid methy...) Show SMILES COC(=O)CCCCCCCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:18:19:22:26.25.24,THB:20:21:24:28.19.27,20:19:22.21.26:24,27:19:22:26.25.24,27:25:22:28.20.19| Show InChI InChI=1S/C24H42N2O3/c1-29-22(27)11-9-7-5-3-2-4-6-8-10-12-25-23(28)26-24-16-19-13-20(17-24)15-21(14-19)18-24/h19-21H,2-18H2,1H3,(H2,25,26,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Department of Entomology and University of California Davis Cancer Center Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase by spectrometric based assay				Bioorg Med Chem 15: 312-23 (2006) Article DOI: 10.1016/j.bmc.2006.09.057 BindingDB Entry DOI: 10.7270/Q26D5SNJ
					More data for this Ligand-Target Pair