BDBM50196668 CHEMBL438838::N-[12-(3-adamantan-1-yl-ureido)-dodecanoyl]-benzenesulfonamide

SMILES: O=C(CCCCCCCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2)NS(=O)(=O)c1ccccc1

InChI Key: InChIKey=XDKZHASGQMWGOM-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50196668   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50196668 (CHEMBL438838 | N-[12-(3-adamantan-1-yl-ureido)-dod...) Show SMILES O=C(CCCCCCCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2)NS(=O)(=O)c1ccccc1 |TLB:16:17:20:24.23.22,THB:18:19:22:26.17.25,18:17:20.19.24:22,25:17:20:24.23.22,25:23:20:26.18.17| Show InChI InChI=1S/C29H45N3O4S/c33-27(32-37(35,36)26-13-9-8-10-14-26)15-11-6-4-2-1-3-5-7-12-16-30-28(34)31-29-20-23-17-24(21-29)19-25(18-23)22-29/h8-10,13-14,23-25H,1-7,11-12,15-22H2,(H,32,33)(H2,30,31,34)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Department of Entomology and University of California Davis Cancer Center Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase by spectrometric based assay				Bioorg Med Chem 15: 312-23 (2006) Article DOI: 10.1016/j.bmc.2006.09.057 BindingDB Entry DOI: 10.7270/Q26D5SNJ
					More data for this Ligand-Target Pair
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50196668 (CHEMBL438838 | N-[12-(3-adamantan-1-yl-ureido)-dod...) Show SMILES O=C(CCCCCCCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2)NS(=O)(=O)c1ccccc1 |TLB:16:17:20:24.23.22,THB:18:19:22:26.17.25,18:17:20.19.24:22,25:17:20:24.23.22,25:23:20:26.18.17| Show InChI InChI=1S/C29H45N3O4S/c33-27(32-37(35,36)26-13-9-8-10-14-26)15-11-6-4-2-1-3-5-7-12-16-30-28(34)31-29-20-23-17-24(21-29)19-25(18-23)22-29/h8-10,13-14,23-25H,1-7,11-12,15-22H2,(H,32,33)(H2,30,31,34)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Department of Entomology and University of California Davis Cancer Center Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase by fluorescent based assay				Bioorg Med Chem 15: 312-23 (2006) Article DOI: 10.1016/j.bmc.2006.09.057 BindingDB Entry DOI: 10.7270/Q26D5SNJ
					More data for this Ligand-Target Pair
Soluble epoxide hydrolase (sEH) (Mus musculus (Mouse))	BDBM50196668 (CHEMBL438838 | N-[12-(3-adamantan-1-yl-ureido)-dod...) Show SMILES O=C(CCCCCCCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2)NS(=O)(=O)c1ccccc1 |TLB:16:17:20:24.23.22,THB:18:19:22:26.17.25,18:17:20.19.24:22,25:17:20:24.23.22,25:23:20:26.18.17| Show InChI InChI=1S/C29H45N3O4S/c33-27(32-37(35,36)26-13-9-8-10-14-26)15-11-6-4-2-1-3-5-7-12-16-30-28(34)31-29-20-23-17-24(21-29)19-25(18-23)22-29/h8-10,13-14,23-25H,1-7,11-12,15-22H2,(H,32,33)(H2,30,31,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Department of Entomology and University of California Davis Cancer Center Curated by ChEMBL					Assay Description Inhibition of mouse soluble epoxide hydrolase by spectrometric based assay				Bioorg Med Chem 15: 312-23 (2006) Article DOI: 10.1016/j.bmc.2006.09.057 BindingDB Entry DOI: 10.7270/Q26D5SNJ
					More data for this Ligand-Target Pair