BDBM50196996 CHEMBL391579::N-(4-(methylsulfonyl)benzyl)-5-cyano-4-hydroxy-6-isopropoxypicolinamide

SMILES: CC(C)Oc1nc(cc(O)c1C#N)C(=O)NCc1ccc(cc1)S(C)(=O)=O

InChI Key: InChIKey=YBWITCNOQPUGCG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50196996   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50196996 (CHEMBL391579 | N-(4-(methylsulfonyl)benzyl)-5-cyan...) Show SMILES CC(C)Oc1nc(cc(O)c1C#N)C(=O)NCc1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C18H19N3O5S/c1-11(2)26-18-14(9-19)16(22)8-15(21-18)17(23)20-10-12-4-6-13(7-5-12)27(3,24)25/h4-8,11H,10H2,1-3H3,(H,20,23)(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of JNK1				Bioorg Med Chem Lett 17: 495-500 (2007) Article DOI: 10.1016/j.bmcl.2006.10.013 BindingDB Entry DOI: 10.7270/Q2JQ10NQ
					More data for this Ligand-Target Pair