BDBM50197977 4-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-pyrazol-5-yl)-N-(3-(pyridin-4-yl)propyl)butanamide::CHEMBL392493

SMILES: Clc1cc(Cl)cc(c1)-c1cc(CCCC(=O)NCCCc2ccncc2)n(n1)-c1ccc2ccccc2c1

InChI Key: InChIKey=NDZSILKFSNYFNX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50197977   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50197977 (4-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...) Show SMILES Clc1cc(Cl)cc(c1)-c1cc(CCCC(=O)NCCCc2ccncc2)n(n1)-c1ccc2ccccc2c1 Show InChI InChI=1S/C31H28Cl2N4O/c32-26-17-25(18-27(33)20-26)30-21-28(37(36-30)29-11-10-23-6-1-2-7-24(23)19-29)8-3-9-31(38)35-14-4-5-22-12-15-34-16-13-22/h1-2,6-7,10-13,15-21H,3-5,8-9,14H2,(H,35,38)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 mins				Bioorg Med Chem Lett 17: 807-13 (2007) Article DOI: 10.1016/j.bmcl.2006.10.060 BindingDB Entry DOI: 10.7270/Q2P84BJD
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50197977 (4-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...) Show SMILES Clc1cc(Cl)cc(c1)-c1cc(CCCC(=O)NCCCc2ccncc2)n(n1)-c1ccc2ccccc2c1 Show InChI InChI=1S/C31H28Cl2N4O/c32-26-17-25(18-27(33)20-26)30-21-28(37(36-30)29-11-10-23-6-1-2-7-24(23)19-29)8-3-9-31(38)35-14-4-5-22-12-15-34-16-13-22/h1-2,6-7,10-13,15-21H,3-5,8-9,14H2,(H,35,38)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytes				Bioorg Med Chem Lett 17: 807-13 (2007) Article DOI: 10.1016/j.bmcl.2006.10.060 BindingDB Entry DOI: 10.7270/Q2P84BJD
					More data for this Ligand-Target Pair