BDBM50198263 CHEMBL399396::ethyl 1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperidine-4-carboxylate

SMILES: CCOC(=O)C1(CCN(Cc2c[nH]c3ccccc23)CC1)c1ccc(Cl)cc1

InChI Key: InChIKey=AZDUCQAJTYHBKO-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50198263   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50198263 (CHEMBL399396 | ethyl 1-((1H-indol-3-yl)methyl)-4-(...) Show SMILES CCOC(=O)C1(CCN(Cc2c[nH]c3ccccc23)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H25ClN2O2/c1-2-28-22(27)23(18-7-9-19(24)10-8-18)11-13-26(14-12-23)16-17-15-25-21-6-4-3-5-20(17)21/h3-10,15,25H,2,11-14,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	58.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL					Assay Description Displacement of [125I]IABN from human dopamine D2L receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 745-9 (2007) Article DOI: 10.1016/j.bmcl.2006.10.076 BindingDB Entry DOI: 10.7270/Q2N879FG
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50198263 (CHEMBL399396 | ethyl 1-((1H-indol-3-yl)methyl)-4-(...) Show SMILES CCOC(=O)C1(CCN(Cc2c[nH]c3ccccc23)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H25ClN2O2/c1-2-28-22(27)23(18-7-9-19(24)10-8-18)11-13-26(14-12-23)16-17-15-25-21-6-4-3-5-20(17)21/h3-10,15,25H,2,11-14,16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	724	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL					Assay Description Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 745-9 (2007) Article DOI: 10.1016/j.bmcl.2006.10.076 BindingDB Entry DOI: 10.7270/Q2N879FG
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50198263 (CHEMBL399396 | ethyl 1-((1H-indol-3-yl)methyl)-4-(...) Show SMILES CCOC(=O)C1(CCN(Cc2c[nH]c3ccccc23)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H25ClN2O2/c1-2-28-22(27)23(18-7-9-19(24)10-8-18)11-13-26(14-12-23)16-17-15-25-21-6-4-3-5-20(17)21/h3-10,15,25H,2,11-14,16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.52E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL					Assay Description Displacement of [125I]IABN from human dopamine D4 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 745-9 (2007) Article DOI: 10.1016/j.bmcl.2006.10.076 BindingDB Entry DOI: 10.7270/Q2N879FG
					More data for this Ligand-Target Pair