BDBM50198356 4-[8-(2,6-dimethylphenylamino)imidazo[1,5-a]-pyrazin-5-yl]benzoic acid::CHEMBL375904

SMILES: Cc1cccc(C)c1Nc1ncc(-c2ccc(cc2)C(O)=O)n2cncc12

InChI Key: InChIKey=WRXRGJHHVGMOKN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198356   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50198356 (4-[8-(2,6-dimethylphenylamino)imidazo[1,5-a]-pyraz...) Show SMILES Cc1cccc(C)c1Nc1ncc(-c2ccc(cc2)C(O)=O)n2cncc12 Show InChI InChI=1S/C21H18N4O2/c1-13-4-3-5-14(2)19(13)24-20-18-10-22-12-25(18)17(11-23-20)15-6-8-16(9-7-15)21(26)27/h3-12H,1-2H3,(H,23,24)(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	235	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Inhibition of cSrc by coupled spectrophotometric enzyme assay				Bioorg Med Chem 15: 868-85 (2006) Article DOI: 10.1016/j.bmc.2006.10.041 BindingDB Entry DOI: 10.7270/Q2DZ094H
					More data for this Ligand-Target Pair