BDBM50198358 CHEMBL227652::N-(2,6-dimethylphenyl)-5-[5-(4-methylpiperazin-1-ylmethyl)thiophen-2-yl]imidazo[1,5-a]pyrazin-8-amine hydrochloride

SMILES: Cc1cccc(C)c1Nc1ncc(C2=CCC(CN3CCCC3)=[S+]2)n2cncc12

InChI Key: InChIKey=LZLRLYRVZHHTNI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198358   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50198358 (CHEMBL227652 | N-(2,6-dimethylphenyl)-5-[5-(4-meth...) Show SMILES Cc1cccc(C)c1Nc1ncc(C2=CCC(CN3CCCC3)=[S+]2)n2cncc12 |c:24,t:14| Show InChI InChI=1S/C23H26N5S/c1-16-6-5-7-17(2)22(16)26-23-20-12-24-15-28(20)19(13-25-23)21-9-8-18(29-21)14-27-10-3-4-11-27/h5-7,9,12-13,15H,3-4,8,10-11,14H2,1-2H3,(H,25,26)/q+1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Inhibition of cSrc in COS7 cells by ELISA				Bioorg Med Chem 15: 868-85 (2006) Article DOI: 10.1016/j.bmc.2006.10.041 BindingDB Entry DOI: 10.7270/Q2DZ094H
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50198358 (CHEMBL227652 | N-(2,6-dimethylphenyl)-5-[5-(4-meth...) Show SMILES Cc1cccc(C)c1Nc1ncc(C2=CCC(CN3CCCC3)=[S+]2)n2cncc12 |c:24,t:14| Show InChI InChI=1S/C23H26N5S/c1-16-6-5-7-17(2)22(16)26-23-20-12-24-15-28(20)19(13-25-23)21-9-8-18(29-21)14-27-10-3-4-11-27/h5-7,9,12-13,15H,3-4,8,10-11,14H2,1-2H3,(H,25,26)/q+1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Inhibition of cSrc by coupled spectrophotometric enzyme assay				Bioorg Med Chem 15: 868-85 (2006) Article DOI: 10.1016/j.bmc.2006.10.041 BindingDB Entry DOI: 10.7270/Q2DZ094H
					More data for this Ligand-Target Pair