BDBM50198364 CHEMBL390367::N-(2-methoxy-6-methylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine

SMILES: COc1cccc(C)c1Nc1ncc(-c2ccccc2)n2cncc12

InChI Key: InChIKey=OTABUBFYJGKYII-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198364   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50198364 (CHEMBL390367 | N-(2-methoxy-6-methylphenyl)-5-phen...) Show SMILES COc1cccc(C)c1Nc1ncc(-c2ccccc2)n2cncc12 Show InChI InChI=1S/C20H18N4O/c1-14-7-6-10-18(25-2)19(14)23-20-17-11-21-13-24(17)16(12-22-20)15-8-4-3-5-9-15/h3-13H,1-2H3,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	693	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Inhibition of cSrc by coupled spectrophotometric enzyme assay				Bioorg Med Chem 15: 868-85 (2006) Article DOI: 10.1016/j.bmc.2006.10.041 BindingDB Entry DOI: 10.7270/Q2DZ094H
					More data for this Ligand-Target Pair