BindingDB logo
myBDB logout

BDBM50198546 (R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)benzylamino)pentan-2-yl)quinoline-3-carboxamide::CHEMBL385876

SMILES: NC(=N)NCCC[C@@H](NC(=O)c1cnc2ccccc2c1)C(=O)NCc1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=ZYTSSSRUWHVSME-HXUWFJFHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198546   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))		BDBM50198546
PNG
((R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)ben...)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)c1cnc2ccccc2c1)C(=O)NCc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C24H25F3N6O2/c25-24(26,27)18-9-7-15(8-10-18)13-32-22(35)20(6-3-11-30-23(28)29)33-21(34)17-12-16-4-1-2-5-19(16)31-14-17/h1-2,4-5,7-10,12,14,20H,3,6,11,13H2,(H,32,35)(H,33,34)(H4,28,29,30)/t20-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 96n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells

Bioorg Med Chem Lett 17: 832-5 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT
More data for this
Ligand-Target Pair