BDBM50198550 (R)-5-guanidino-2-(2-(naphthalen-1-yl)acetamido)-N-(4-(trifluoromethyl)benzyl)pentanamide::CHEMBL217193

SMILES: NC(=N)NCCC[C@@H](NC(=O)Cc1cccc2ccccc12)C(=O)NCc1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=SAQPKSYQYLDSSI-JOCHJYFZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198550   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50198550 ((R)-5-guanidino-2-(2-(naphthalen-1-yl)acetamido)-N...) Show SMILES NC(=N)NCCC[C@@H](NC(=O)Cc1cccc2ccccc12)C(=O)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C26H28F3N5O2/c27-26(28,29)20-12-10-17(11-13-20)16-33-24(36)22(9-4-14-32-25(30)31)34-23(35)15-19-7-3-6-18-5-1-2-8-21(18)19/h1-3,5-8,10-13,22H,4,9,14-16H2,(H,33,36)(H,34,35)(H4,30,31,32)/t22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	243	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Functional antagonism of MCH-R1 expressed in HEK293 cells				Bioorg Med Chem Lett 17: 832-5 (2007) Article DOI: 10.1016/j.bmcl.2006.10.056 BindingDB Entry DOI: 10.7270/Q2GH9HMT
					More data for this Ligand-Target Pair