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BDBM50198556 (R)-2-(2-(1H-indol-2-yl)acetamido)-5-guanidino-N-(4-(trifluoromethyl)benzyl)pentanamide::CHEMBL384734

SMILES: NC(=N)NCCC[C@@H](NC(=O)Cc1cc2ccccc2[nH]1)C(=O)NCc1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=NLLMFKLNLNOLBL-HXUWFJFHSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198556   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))		BDBM50198556
PNG
((R)-2-(2-(1H-indol-2-yl)acetamido)-5-guanidino-N-(...)
Show SMILES NC(=N)NCCC[C@@H](NC(=O)Cc1cc2ccccc2[nH]1)C(=O)NCc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C24H27F3N6O2/c25-24(26,27)17-9-7-15(8-10-17)14-31-22(35)20(6-3-11-30-23(28)29)33-21(34)13-18-12-16-4-1-2-5-19(16)32-18/h1-2,4-5,7-10,12,20,32H,3,6,11,13-14H2,(H,31,35)(H,33,34)(H4,28,29,30)/t20-/m1/s1
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n/an/a 512n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional antagonism of MCH-R1 expressed in HEK293 cells

Bioorg Med Chem Lett 17: 832-5 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.056
BindingDB Entry DOI: 10.7270/Q2GH9HMT
More data for this
Ligand-Target Pair