BDBM50198660 CHEMBL3928231

SMILES: CCCCCCn1c(ccc1-c1ccc2oc(=O)ccc2c1)C#N

InChI Key: InChIKey=JPYHJUWFOMIQNC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198660   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50198660 (CHEMBL3928231) Show SMILES CCCCCCn1c(ccc1-c1ccc2oc(=O)ccc2c1)C#N Show InChI InChI=1S/C20H20N2O2/c1-2-3-4-5-12-22-17(14-21)8-9-18(22)15-6-10-19-16(13-15)7-11-20(23)24-19/h6-11,13H,2-5,12H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase expression after 24 hrs by alkaline...				Bioorg Med Chem 24: 5602-5610 (2016) Article DOI: 10.1016/j.bmc.2016.09.020 BindingDB Entry DOI: 10.7270/Q2R49SRM
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50198660 (CHEMBL3928231) Show SMILES CCCCCCn1c(ccc1-c1ccc2oc(=O)ccc2c1)C#N Show InChI InChI=1S/C20H20N2O2/c1-2-3-4-5-12-22-17(14-21)8-9-18(22)15-6-10-19-16(13-15)7-11-20(23)24-19/h6-11,13H,2-5,12H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Displacement of [1,2,6,7-3H]progesterone from recombinant human GST-tagged PR-LBD (675 to 933 residues) expressed in baculovirus-infected insect cell...				Bioorg Med Chem 24: 5602-5610 (2016) Article DOI: 10.1016/j.bmc.2016.09.020 BindingDB Entry DOI: 10.7270/Q2R49SRM
					More data for this Ligand-Target Pair