BDBM50198678 CHEMBL3891045

SMILES: O=c1ccc2cc(ccc2o1)-c1ccc([nH]1)C#N

InChI Key: InChIKey=TUKRWKJJSRKXRW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198678   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50198678 (CHEMBL3891045) Show SMILES O=c1ccc2cc(ccc2o1)-c1ccc([nH]1)C#N Show InChI InChI=1S/C14H8N2O2/c15-8-11-3-4-12(16-11)9-1-5-13-10(7-9)2-6-14(17)18-13/h1-7,16H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase expression after 24 hrs by alkaline...				Bioorg Med Chem 24: 5602-5610 (2016) Article DOI: 10.1016/j.bmc.2016.09.020 BindingDB Entry DOI: 10.7270/Q2R49SRM
					More data for this Ligand-Target Pair