BDBM50199315 CHEMBL384577::N-iso-Butyloxycarbonyl-3-(4-imidazol-1-ylmethylphenyl)-5-iso-butylthiophene-2-sulfonamide

SMILES: CC(C)COC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1

InChI Key: InChIKey=UZDLZKANCYDPSR-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50199315   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II receptor (Homo sapiens (Human))	BDBM50199315 (CHEMBL384577 | N-iso-Butyloxycarbonyl-3-(4-imidazo...) Show SMILES CC(C)COC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C23H29N3O4S2/c1-16(2)11-20-12-21(19-7-5-18(6-8-19)13-26-10-9-24-15-26)22(31-20)32(28,29)25-23(27)30-14-17(3)4/h5-10,12,15-17H,11,13-14H2,1-4H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]Ang2 from AT2 receptor in pig uterus membrane				J Med Chem 49: 7160-8 (2006) Article DOI: 10.1021/jm0606185 BindingDB Entry DOI: 10.7270/Q21C1WHK
					More data for this Ligand-Target Pair
Angiotensin II AT2 (RAT)	BDBM50199315 (CHEMBL384577 | N-iso-Butyloxycarbonyl-3-(4-imidazo...) Show SMILES CC(C)COC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C23H29N3O4S2/c1-16(2)11-20-12-21(19-7-5-18(6-8-19)13-26-10-9-24-15-26)22(31-20)32(28,29)25-23(27)30-14-17(3)4/h5-10,12,15-17H,11,13-14H2,1-4H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]Ang2 from AT2 receptor in rat liver membrane				J Med Chem 49: 7160-8 (2006) Article DOI: 10.1021/jm0606185 BindingDB Entry DOI: 10.7270/Q21C1WHK
					More data for this Ligand-Target Pair