BDBM50199319 CHEMBL217084::N-(4,4,4-triflouro-butyloxycarbonyl)-3-(4-imidazol-1-ylmethylphenyl)-5-isobutylthiophene-2-sulfonamide

SMILES: CC(C)Cc1cc(c(s1)S(=O)(=O)NC(=O)OCCCC(F)(F)F)-c1ccc(Cn2ccnc2)cc1

InChI Key: InChIKey=XHNUQRWWXICBMG-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50199319   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II AT2 (RAT)	BDBM50199319 (CHEMBL217084 | N-(4,4,4-triflouro-butyloxycarbonyl...) Show SMILES CC(C)Cc1cc(c(s1)S(=O)(=O)NC(=O)OCCCC(F)(F)F)-c1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C23H26F3N3O4S2/c1-16(2)12-19-13-20(18-6-4-17(5-7-18)14-29-10-9-27-15-29)21(34-19)35(31,32)28-22(30)33-11-3-8-23(24,25)26/h4-7,9-10,13,15-16H,3,8,11-12,14H2,1-2H3,(H,28,30)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]Ang2 from AT2 receptor in rat liver membrane				J Med Chem 49: 7160-8 (2006) Article DOI: 10.1021/jm0606185 BindingDB Entry DOI: 10.7270/Q21C1WHK
					More data for this Ligand-Target Pair
Angiotensin II receptor (Homo sapiens (Human))	BDBM50199319 (CHEMBL217084 | N-(4,4,4-triflouro-butyloxycarbonyl...) Show SMILES CC(C)Cc1cc(c(s1)S(=O)(=O)NC(=O)OCCCC(F)(F)F)-c1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C23H26F3N3O4S2/c1-16(2)12-19-13-20(18-6-4-17(5-7-18)14-29-10-9-27-15-29)21(34-19)35(31,32)28-22(30)33-11-3-8-23(24,25)26/h4-7,9-10,13,15-16H,3,8,11-12,14H2,1-2H3,(H,28,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]Ang2 from AT2 receptor in pig uterus membrane				J Med Chem 49: 7160-8 (2006) Article DOI: 10.1021/jm0606185 BindingDB Entry DOI: 10.7270/Q21C1WHK
					More data for this Ligand-Target Pair