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SMILES: CCN(C1CCN(CC)C1)c1cc(OC)cc2c(O)cc(nc12)C(=O)Nc1ccc(cc1)N1CCOCC1

InChI Key: InChIKey=QGPQKWYMNWOLLI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199562   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))		BDBM50199562
PNG
(8-[ethyl-(1-ethyl-pyrrolidin-3-yl)-amino]-6-methox...)
Show SMILES CCN(C1CCN(CC)C1)c1cc(OC)cc2c(O)cc(nc12)C(=O)Nc1ccc(cc1)N1CCOCC1
Show InChI InChI=1S/C29H37N5O4/c1-4-32-11-10-22(19-32)34(5-2)26-17-23(37-3)16-24-27(35)18-25(31-28(24)26)29(36)30-20-6-8-21(9-7-20)33-12-14-38-15-13-33/h6-9,16-18,22H,4-5,10-15,19H2,1-3H3,(H,30,36)(H,31,35)
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Article
PubMed
 170n/an/an/an/an/an/an/an/a



AstraZeneca Pharmaceuticals LP

Curated by ChEMBL


Assay Description
Displacement of [3H]GR125743 from 5HT1B receptor transfected in CHO cells

Bioorg Med Chem 15: 939-50 (2006)


Article DOI: 10.1016/j.bmc.2006.10.037
BindingDB Entry DOI: 10.7270/Q2445M3X
More data for this
Ligand-Target Pair