BDBM50200615 CHEMBL240941::N-isopropyl-2-(3-{1-[3-(5-methoxy-2-methylphenoxy)-4-methyl-pentyl]-piperidin-4-yl}-2-oxo-2,3-dihydro-benzimidazol-1-yl)-acetamide

SMILES: COc1ccc(C)c(OC(CCN2CCC(CC2)n2c3ccccc3n(CC(=O)NC(C)C)c2=O)C(C)C)c1

InChI Key: InChIKey=BHXTYLLOXRKFJS-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50200615   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50200615 (CHEMBL240941 | N-isopropyl-2-(3-{1-[3-(5-methoxy-2...) Show SMILES COc1ccc(C)c(OC(CCN2CCC(CC2)n2c3ccccc3n(CC(=O)NC(C)C)c2=O)C(C)C)c1 |w:9.8| Show InChI InChI=1S/C31H44N4O4/c1-21(2)28(39-29-19-25(38-6)12-11-23(29)5)15-18-33-16-13-24(14-17-33)35-27-10-8-7-9-26(27)34(31(35)37)20-30(36)32-22(3)4/h7-12,19,21-22,24,28H,13-18,20H2,1-6H3,(H,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cells				Bioorg Med Chem 15: 1828-47 (2007) Article DOI: 10.1016/j.bmc.2006.11.030 BindingDB Entry DOI: 10.7270/Q27S7NF2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50200615 (CHEMBL240941 | N-isopropyl-2-(3-{1-[3-(5-methoxy-2...) Show SMILES COc1ccc(C)c(OC(CCN2CCC(CC2)n2c3ccccc3n(CC(=O)NC(C)C)c2=O)C(C)C)c1 |w:9.8| Show InChI InChI=1S/C31H44N4O4/c1-21(2)28(39-29-19-25(38-6)12-11-23(29)5)15-18-33-16-13-24(14-17-33)35-27-10-8-7-9-26(27)34(31(35)37)20-30(36)32-22(3)4/h7-12,19,21-22,24,28H,13-18,20H2,1-6H3,(H,32,36)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	238	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human MOP receptor expressed in CHOK1 cells				Bioorg Med Chem 15: 1828-47 (2007) Article DOI: 10.1016/j.bmc.2006.11.030 BindingDB Entry DOI: 10.7270/Q27S7NF2
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50200615 (CHEMBL240941 | N-isopropyl-2-(3-{1-[3-(5-methoxy-2...) Show SMILES COc1ccc(C)c(OC(CCN2CCC(CC2)n2c3ccccc3n(CC(=O)NC(C)C)c2=O)C(C)C)c1 |w:9.8| Show InChI InChI=1S/C31H44N4O4/c1-21(2)28(39-29-19-25(38-6)12-11-23(29)5)15-18-33-16-13-24(14-17-33)35-27-10-8-7-9-26(27)34(31(35)37)20-30(36)32-22(3)4/h7-12,19,21-22,24,28H,13-18,20H2,1-6H3,(H,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd. Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 2 hrs				Bioorg Med Chem 15: 1828-47 (2007) Article DOI: 10.1016/j.bmc.2006.11.030 BindingDB Entry DOI: 10.7270/Q27S7NF2
					More data for this Ligand-Target Pair