Found 4 hits for monomerid = 50201211 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Rhodesain
(Trypanosoma brucei rhodesiense) | BDBM50201211
(CHEMBL3930083)Show SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCc1ccccc1)\C=C\[N+]([O-])=O |r| Show InChI InChI=1S/C25H31N3O5/c1-19(2)17-23(27-25(30)33-18-21-11-7-4-8-12-21)24(29)26-22(15-16-28(31)32)14-13-20-9-5-3-6-10-20/h3-12,15-16,19,22-23H,13-14,17-18H2,1-2H3,(H,26,29)(H,27,30)/b16-15+/t22-,23-/m0/s1 | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Jaume I
Curated by ChEMBL
| Assay Description
Inhibition of Trypanosoma brucei rhodesiense rhodesain expressed in Pichia pastoris using Cbz-Phe-Arg-AMC as substrate after 15 to 30 mins by fluores... |
ACS Med Chem Lett 7: 1073-1076 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00276
BindingDB Entry DOI: 10.7270/Q2M32XR1 |
More data for this
Ligand-Target Pair | |
Cruzipain
(Trypanosoma cruzi) | BDBM50201211
(CHEMBL3930083)Show SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCc1ccccc1)\C=C\[N+]([O-])=O |r| Show InChI InChI=1S/C25H31N3O5/c1-19(2)17-23(27-25(30)33-18-21-11-7-4-8-12-21)24(29)26-22(15-16-28(31)32)14-13-20-9-5-3-6-10-20/h3-12,15-16,19,22-23H,13-14,17-18H2,1-2H3,(H,26,29)(H,27,30)/b16-15+/t22-,23-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Jaume I
Curated by ChEMBL
| Assay Description
Inhibition of Trypanosoma cruzi cruzain |
ACS Med Chem Lett 7: 1073-1076 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00276
BindingDB Entry DOI: 10.7270/Q2M32XR1 |
More data for this
Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50201211
(CHEMBL3930083)Show SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCc1ccccc1)\C=C\[N+]([O-])=O |r| Show InChI InChI=1S/C25H31N3O5/c1-19(2)17-23(27-25(30)33-18-21-11-7-4-8-12-21)24(29)26-22(15-16-28(31)32)14-13-20-9-5-3-6-10-20/h3-12,15-16,19,22-23H,13-14,17-18H2,1-2H3,(H,26,29)(H,27,30)/b16-15+/t22-,23-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Jaume I
Curated by ChEMBL
| Assay Description
Inhibition of human cathepsin L |
ACS Med Chem Lett 7: 1073-1076 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00276
BindingDB Entry DOI: 10.7270/Q2M32XR1 |
More data for this
Ligand-Target Pair | |
Cathepsin B
(Homo sapiens (Human)) | BDBM50201211
(CHEMBL3930083)Show SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCc1ccccc1)\C=C\[N+]([O-])=O |r| Show InChI InChI=1S/C25H31N3O5/c1-19(2)17-23(27-25(30)33-18-21-11-7-4-8-12-21)24(29)26-22(15-16-28(31)32)14-13-20-9-5-3-6-10-20/h3-12,15-16,19,22-23H,13-14,17-18H2,1-2H3,(H,26,29)(H,27,30)/b16-15+/t22-,23-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 72 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Jaume I
Curated by ChEMBL
| Assay Description
Inhibition of human cathepsin B |
ACS Med Chem Lett 7: 1073-1076 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00276
BindingDB Entry DOI: 10.7270/Q2M32XR1 |
More data for this
Ligand-Target Pair | |
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