BDBM50201233 4-(2,4-dichloro-5-methoxyphenylamino)-7-(4-(4-methylpiperazin-1-yl)but-1-ynyl)quinoline-3-carbonitrile::CHEMBL240415

SMILES: COc1cc(Nc2c(cnc3cc(ccc23)C#CCCN2CCN(C)CC2)C#N)c(Cl)cc1Cl

InChI Key: InChIKey=CEWKJJLIUMKWDY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201233   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50201233 (4-(2,4-dichloro-5-methoxyphenylamino)-7-(4-(4-meth...) Show SMILES COc1cc(Nc2c(cnc3cc(ccc23)C#CCCN2CCN(C)CC2)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C26H25Cl2N5O/c1-32-9-11-33(12-10-32)8-4-3-5-18-6-7-20-23(13-18)30-17-19(16-29)26(20)31-24-15-25(34-2)22(28)14-21(24)27/h6-7,13-15,17H,4,8-12H2,1-2H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of Src activity				Bioorg Med Chem Lett 17: 1358-61 (2007) Article DOI: 10.1016/j.bmcl.2006.11.077 BindingDB Entry DOI: 10.7270/Q2SJ1K7T
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Rattus norvegicus)	BDBM50201233 (4-(2,4-dichloro-5-methoxyphenylamino)-7-(4-(4-meth...) Show SMILES COc1cc(Nc2c(cnc3cc(ccc23)C#CCCN2CCN(C)CC2)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C26H25Cl2N5O/c1-32-9-11-33(12-10-32)8-4-3-5-18-6-7-20-23(13-18)30-17-19(16-29)26(20)31-24-15-25(34-2)22(28)14-21(24)27/h6-7,13-15,17H,4,8-12H2,1-2H3,(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of Src in rat fibroblasts				Bioorg Med Chem Lett 17: 1358-61 (2007) Article DOI: 10.1016/j.bmcl.2006.11.077 BindingDB Entry DOI: 10.7270/Q2SJ1K7T
					More data for this Ligand-Target Pair