BDBM50201236 4-(2,4-dichlorophenylamino)-6-methoxy-7-(4-(4-methylpiperazin-1-yl)but-1-ynyl)quinoline-3-carbonitrile::CHEMBL240829

SMILES: COc1cc2c(Nc3ccc(Cl)cc3Cl)c(cnc2cc1C#CCCN1CCN(C)CC1)C#N

InChI Key: InChIKey=GAPDGBDSBXIFHK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201236   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Rattus norvegicus)	BDBM50201236 (4-(2,4-dichlorophenylamino)-6-methoxy-7-(4-(4-meth...) Show SMILES COc1cc2c(Nc3ccc(Cl)cc3Cl)c(cnc2cc1C#CCCN1CCN(C)CC1)C#N Show InChI InChI=1S/C26H25Cl2N5O/c1-32-9-11-33(12-10-32)8-4-3-5-18-13-24-21(15-25(18)34-2)26(19(16-29)17-30-24)31-23-7-6-20(27)14-22(23)28/h6-7,13-15,17H,4,8-12H2,1-2H3,(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of Src in rat fibroblasts				Bioorg Med Chem Lett 17: 1358-61 (2007) Article DOI: 10.1016/j.bmcl.2006.11.077 BindingDB Entry DOI: 10.7270/Q2SJ1K7T
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50201236 (4-(2,4-dichlorophenylamino)-6-methoxy-7-(4-(4-meth...) Show SMILES COc1cc2c(Nc3ccc(Cl)cc3Cl)c(cnc2cc1C#CCCN1CCN(C)CC1)C#N Show InChI InChI=1S/C26H25Cl2N5O/c1-32-9-11-33(12-10-32)8-4-3-5-18-13-24-21(15-25(18)34-2)26(19(16-29)17-30-24)31-23-7-6-20(27)14-22(23)28/h6-7,13-15,17H,4,8-12H2,1-2H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of Src activity				Bioorg Med Chem Lett 17: 1358-61 (2007) Article DOI: 10.1016/j.bmcl.2006.11.077 BindingDB Entry DOI: 10.7270/Q2SJ1K7T
					More data for this Ligand-Target Pair