BDBM50201318 1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(3-fluorophenyl)urea::CHEMBL231209
SMILES: Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12
InChI Key: InChIKey=RIUZPIBUSOHUKF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50201318 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50201318
![PNG](/data/jpeg/tenK5020/BindingDB_50201318.png) (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...)Show SMILES Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12 Show InChI InChI=1S/C20H15FN4OS/c21-13-2-1-3-15(10-13)25-20(26)24-14-6-4-12(5-7-14)16-11-27-17-8-9-23-19(22)18(16)17/h1-11H,(H2,22,23)(H2,24,25,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 147 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of human KDR phosphorylation in NIH3T3 cells |
Bioorg Med Chem Lett 17: 1246-9 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50201318
![PNG](/data/jpeg/tenK5020/BindingDB_50201318.png) (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...)Show SMILES Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12 Show InChI InChI=1S/C20H15FN4OS/c21-13-2-1-3-15(10-13)25-20(26)24-14-6-4-12(5-7-14)16-11-27-17-8-9-23-19(22)18(16)17/h1-11H,(H2,22,23)(H2,24,25,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of KDR |
Bioorg Med Chem Lett 17: 1246-9 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS |
More data for this Ligand-Target Pair | |