BDBM50201444 3-amino-N-(diaminomethylene)-5-(3-fluorophenyl)furan-2-carboxamide::CHEMBL441127

SMILES: NC(=N)NC(=O)c1oc(cc1N)-c1cccc(F)c1

InChI Key: InChIKey=MOZGLRKRGKZGSC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201444   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/hydrogen exchanger 1 (Homo sapiens (Human))	BDBM50201444 (3-amino-N-(diaminomethylene)-5-(3-fluorophenyl)fur...) Show SMILES NC(=N)NC(=O)c1oc(cc1N)-c1cccc(F)c1 Show InChI InChI=1S/C12H11FN4O2/c13-7-3-1-2-6(4-7)9-5-8(14)10(19-9)11(18)17-12(15)16/h1-5H,14H2,(H4,15,16,17,18)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of human NHE1 expressed in PS120 cells				Bioorg Med Chem Lett 17: 1291-5 (2007) Article DOI: 10.1016/j.bmcl.2006.12.012 BindingDB Entry DOI: 10.7270/Q2MW2GS1
					More data for this Ligand-Target Pair