BDBM50201449 CHEMBL232179::N-(diaminomethylene)-5-(2,5-dichlorophenyl)-3-(N-methylacetamido)furan-2-carboxamide

SMILES: CN(C(C)=O)c1cc(oc1C(=O)NC(N)=N)-c1cc(Cl)ccc1Cl

InChI Key: InChIKey=SIANDLWYWQYUIX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201449   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/hydrogen exchanger 1 (Homo sapiens (Human))	BDBM50201449 (CHEMBL232179 | N-(diaminomethylene)-5-(2,5-dichlor...) Show SMILES CN(C(C)=O)c1cc(oc1C(=O)NC(N)=N)-c1cc(Cl)ccc1Cl Show InChI InChI=1S/C15H14Cl2N4O3/c1-7(22)21(2)11-6-12(9-5-8(16)3-4-10(9)17)24-13(11)14(23)20-15(18)19/h3-6H,1-2H3,(H4,18,19,20,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of human NHE1 expressed in PS120 cells				Bioorg Med Chem Lett 17: 1291-5 (2007) Article DOI: 10.1016/j.bmcl.2006.12.012 BindingDB Entry DOI: 10.7270/Q2MW2GS1
					More data for this Ligand-Target Pair