BDBM50201453 CHEMBL396616::N-(diaminomethylene)-3-(methylamino)-5-phenylfuran-2-carboxamide

SMILES: CNc1cc(oc1C(=O)NC(N)=N)-c1ccccc1

InChI Key: InChIKey=KXXYGWORKRDAFB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201453   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/hydrogen exchanger 1 (Homo sapiens (Human))	BDBM50201453 (CHEMBL396616 | N-(diaminomethylene)-3-(methylamino...) Show SMILES CNc1cc(oc1C(=O)NC(N)=N)-c1ccccc1 Show InChI InChI=1S/C13H14N4O2/c1-16-9-7-10(8-5-3-2-4-6-8)19-11(9)12(18)17-13(14)15/h2-7,16H,1H3,(H4,14,15,17,18)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of human NHE1 expressed in PS120 cells				Bioorg Med Chem Lett 17: 1291-5 (2007) Article DOI: 10.1016/j.bmcl.2006.12.012 BindingDB Entry DOI: 10.7270/Q2MW2GS1
					More data for this Ligand-Target Pair